About Help FAQ

Symbol
Name
ID

Mapk1
mitogen-activated protein kinase 1
MGI:1346858

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Recurrent otitis media
Disease(s) Associated with MAPK1	Recurrent otitis media
Noonan syndrome 13

Mouse Phenotypes		decreased T cell proliferation	abnormal thymus morphology	abnormal positive T cell selection	decreased double-positive T cell number	increased double-positive T cell number	abnormal T cell subpopulation ratio	decreased CD4-positive, alpha-beta T cell number	decreased CD8-positive, alpha-beta T cell number
Availability	Mouse Genotype	decreased T cell proliferation	abnormal thymus morphology	abnormal positive T cell selection	decreased double-positive T cell number	increased double-positive T cell number	abnormal T cell subpopulation ratio	decreased CD4-positive, alpha-beta T cell number	decreased CD8-positive, alpha-beta T cell number
	Mapk1^tm1.1Hed/Mapk1^tm1.1Hed Tg(Lck-cre)1Cwi/0 (conditional)
	Mapk1^tm1Gela/Mapk1^tm1Gela H2az2^{Tg(Wnt1-cre)11Rth}/0 (conditional)
	Mapk1^tm1Hed/Mapk1^tm1Hed Tg(Lck-cre)1Cwi/0 (conditional)
	Mapk1^tm1Hed/Mapk1^tm1Hed Tg(Cd4-cre)1Cwi/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23